The Leishmania tarentolae Spliced Leader Contains Determinants for Association with Polysomes
نویسندگان
چکیده
منابع مشابه
The Leishmania tarentolae spliced leader contains determinants for association with polysomes.
In kinetoplastids, every nuclear-derived mRNA contains an identical 39-nucleotide (nt) spliced leader at its 5'-terminus. The spliced leader is derived from substrate spliced leader RNA and joined to pre-mRNA by trans-splicing, thus providing mature mRNAs with an m7G cap and additional methylations referred to as cap 4. It was shown previously that mutations spanning nucleotides 10-39 of the sp...
متن کاملSpliced leader trans-splicing
on the forests, wildlife, and indigenous people of this area, WWF warns. It is not necessary to use this area as there is already a total of 2.3 million hectares of idle or derelict land available for palm oil plantations in Kalimantan, an area greater than the proposed plantation, WWF points out. In addition, oil palm is not recommended for planting in areas more than 200 metres above sea leve...
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Taxonomic studies and classification of Leishmania species have developed rapidly in recent years, but controversy still surrounds the relationships between those species infecting lizards and those infecting mammals. Some authorities maintain that the leishmanias o f lizards form a sufficiently distinct group to be ranked as a separate genus - Sauroleishmania(1,2) - while Wallbanks et al. have...
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The intracellular distribution of glutaminyl-tRNA synthetases and their role in mitochondrial tRNA import were evaluated in the ancient eukaryote Leishmania tarentolae. The following results were obtained: (i) Glutaminyl-tRNA synthetase was detected in leishmanial mitochondria. This was unexpected because it has been postulated that, in organelles, Gln-tRNAGln is not formed by direct acylation ...
متن کاملTrypanosome spliced-leader-associated RNA (SLA1) localization and implications for spliced-leader RNA biogenesis.
Spliced-leader-associated RNA (SLA1) guides the pseudouridylation at position -12 (relative to the 5' splice site) of the spliced-leader (SL) RNA in all trypanosomatid species. Nevertheless, the exact role of this RNA is currently unknown. Here, we demonstrate that the absence of pseudouridine on Leptomonas collosoma SL RNA has only a minor effect on the ability of this RNA to function in trans...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2003
ISSN: 0021-9258
DOI: 10.1074/jbc.m304295200